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‘Antenatal care’ isn’t just medical appointments - it can also include antenatal or parenting classes if they’ve been recommended by a doctor or midwife (1)
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RESULTS: Seventy-five patients were identified of which 57% reported any improvement in seizure control and 33% reported a >50% reduction in seizures (responders). If the family had moved to CO for OCE (Oral Cannabis Extracts) treatment, the responder rate was 47% vs. 22% for children who already were in CO. The responder rate varied based on epilepsy syndrome: Dravet 23%, Doose 0%, and Lennox-Gastaut syndrome (LGS) 88.9%. The background EEG of the 8 responders where EEG data were available was not improved. Additional benefits reported included: improved behavior/alertness (33%), improved language (10%), and improved motor skills (10%). Adverse events (AEs) occurred in 44% of patients including increased seizures (13%) and somnolence/fatigue (12%). Rare adverse events included developmental regression, abnormal movements, status epilepticus requiring intubation, and death. SIGNIFICANCE: Our retrospective study of OCE use in pediatric patients with epilepsy demonstrates that some families reported patient improvement with treatment; however, we also found a variety of challenges and possible confounding factors in studying OCE retrospectively in an open-labeled fashion. We strongly support the need for controlled, blinded studies to evaluate the efficacy and safety of OCE for treatment of pediatric epilepsies using accurate seizure counts, formal neurocognitive assessments, as well as EEG as a biomarker. This study provides Class III evidence that OCE is well tolerated by children and adolescents with epilepsy. (1)
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OCCSKSARGEN contributed 2.76 percent to the country's Gross Domestic Product. In 2013, GRDP grew by 8.40 percent. Agriculture, Hunting, Forestry and Fishing sector which accounted for 28.57 percent of the regional economy recorded an 3.50 percent increment in 2013 (1)
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1Novak A: The Future of the Mandatory Death Penalty in Malaysia and Singapore: ""Asian Values"" and Abolition in Comparative Perspective, with Implications for Indonesia. Academiaedu, 2015. Available from: https://www.academia.edu/7092813/The_Future_of_the_Mandatory_Death_Penalty_in_Malaysia_and_Singapore_Asian_Values_and_Abolition_in_Comparative_Perspective_with_Implications_for_Indonesia [last accessed 28 April 2015].
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1Gilman J, Kuster J, Lee S, Lee M, Kim B, Makris N, van der Kouwe A, Blood A and Breiter H: Cannabis Use Is Quantitatively Associated with Nucleus Accumbens and Amygdala Abnormalities in Young Adult Recreational Users. Journal of Neuroscience 34: 5529-5538, 2014.
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The results of this study indicate that in young, recreational marijuana users, structural abnormalities in gray matter density, volume, and shape of the nucleus accumbens and amygdala can be observed. Pending confirmation in other cohorts of marijuana users, the present findings suggest that further study of marijuana effects are needed to help inform discussion about the legaliza- tion of marijuana. These results extend prior studies showing that drugs of abuse that are known to elevate DA release are associated with structural abnormalities in the brain and related disrup- tions in behavior (Makris et al., 2004; Makris et al., 2008). The multimodal convergence of these findings also points to the salience of structural differences in the brain related to drug exposure and strongly argues that human addiction research, if not all psychiatric study, must move past a predominant focus on neurotransmission. (1)
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That statement comes with an exclamation point on Thursday in particular, with a new paper out in Science that confirms many of Francis's ideas and applies them not just to extreme winter weather but, in some ways even more troubling, to extremes of summer heat.The new paper, by Dim Coumou and two colleagues at the Potsdam Institute for Climate Impact Research and the University of Potsdam in Germany, finds that the melting Arctic is indeed messing with the jet stream (as well as the broader atmospheric circulation) and our weather. But it also goes further by asserting that there's a strong effect in the summer in particular. The progress of weather is slowing during the summer, the authors assert, and the result could be a very deadly one including ""more persistent heat waves in recent summers.""Or as the researchers put it, a weaker jet stream and atmospheric circulation in the summer, caused by a reduced differential in temperature between the equator and the north pole as the Arctic warms faster than the mid-latitudes, ""has made weather more persistent and hence favored the occurrence of prolonged heat extremes.""The study, said Francis who is familiar with the work but was not involved in the research not only confirms her broad idea, but does so by examining a new and more detailed mechanism. The Potsdam researchers looked at an atmospheric feature called ""eddy kinetic energy,"" which, as Francis explained, basically refers to the winds swirling around regions of high and low pressure. Those winds have decreased, the paper finds.""That's why they're saying that it's more likely to have summer extreme events,"" Francis said. ""Because the weather just is not changing as much, and the weather systems themselves are just more stagnant and lethargic.""The new study points in particular to the devastating 2010 summer heat wave in Russia. ""By late July and early August, numerous cities witnessed a crescendo of record breaking daily readings near 40 C, more than +10 C warmer than what would normally have been experienced at this warmest time of year,"" noted the National Oceanic and Atmospheric Administration at the time. The resulting death toll could have been as high as 55,000.Page 2 of 2 - So how did such an extreme come about? The new paper notes that ""the record breaking July temperatures over Moscow were associated with extremely low [eddy kinetic energy]."" In other words, there was just not enough circulation of air to bring in cooler temperatures.""If this whole circulation slows down and there's less energy in these storms, then basically we get more persistent weather situations, which can lead to some extreme heat waves,"" said Stefan Rahmstorf, also a researcher at the Potsdam Institute for Climate Impact Research but not one of the study's authors.So what's the upshot for the ongoing debate over whether the Arctic is, indeed, messing with weather in the mid-latitudes all over the globe? ""I think the balance of evidence is kinds of moving towards confirming that there is this influence of the Arctic,"" said Rahmstorf.""It's making the pile of evidence I think look pretty substantial,"" added Francis.That doesn't mean the debate is over or clinched. But it does mean that questions over precisely how the rapidly melting Arctic is feeding back into the weather we all experience are getting more pressing and pertinent than ever. (1)
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it seems it was the playwright, Eduard Vidal I Valenciano, who in 1864 first coined the term renaixença (rebirth) which was to stick (1)
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based on the pursuit of vertigo and which consist of an attempt to momentarily destroy the stability of perception and inflict a kind of voluptuous panic upon an otherwise lucid mind. In all cases, it is a question of surrendering to a kind of spasm, seizure, or shock which destroys reality with sovereign brusqueness (1)
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In 2012, nearly 3/4 of students (72%) have consumed alcohol (more than just a few sips) by the end "